DMT (Dimethyltryptamine) is a short-acting, albeit powerful psychedelic drug in the 
tryptamine family. Additionally, the use of Monoamine oxidase inhibitors (MAOIs), an older class of anti-depressant drugs, has been found to increase the effects of DMT. This chemical structure of DMT has the same or similar chemical structure as the natural neurotransmitter serotonin and the hormone melatonin found in the brain. Our bodies actually produce DMT, but science hasn’t determined its purpose thus far. It is derived from the essential amino acid tryptophan and produced by the same enzyme INMT during the body’s normal metabolism. Some researches have postulated that brain’s production of DMT may be related to the organic cause of some mental illness.
Adolescents are naturally curious creatures. They want to know about the world that they live in and they want to understand why it is the way it is. Developmentally this leads to a natural curiosity about the nature of the world and spiritual matters. During the 1960s, well-respected researchers looked into the potential of psychedelic drugs to treat mental illness, including depression. The ’60s generation took this as a cue to experiment with their minds. What we have learned since then is such experimentation is potentially dangerous and harmful, especially for those with a latent tendency toward depression, anxiety, schizophrenia and other forms of mental illness.
Psychedelic drugs have a distinct effect on brain chemistry. Some of them have chemical structures similar to natural neurotransmitters and almost all of them are classified as alkaloid. Historically, psychedelic drugs have been used by ancient cultures for spiritual practice and ceremony. And science has used psychedelic drugs for research.
However, psychedelics are significantly abused.
One of the most dangerous components of psychedelic drugs is the potential negative effect on people already vulnerable to mental illness. The user is, in effect, playing with his or her brain chemistry without direct knowledge of any short- or long-term effects these drugs may have. And someone who has an undiagnosed or untreated mental illness can adversely affect his or her mental health with the use of psychedelic drugs, or any drugs for that matter. Drugs like DMT, though old, are no different. DMT works fast, it has an intense effect that lasts for 15 minutes but purportedly feels like several hours. This can be an overwhelming experience, especially in cases of untreated or undiagnosed mental illness.
The bottom like is this: Experimenting with your mind is dangerous. Curious or not, this type of psychological misadventure is not worth the risk and the potential fallout.
